They react in this way with all bases, both organic (for example, the amines) and inorganic. Their reactions with bases, called "neutralizations", are accompanied by … Its melting point is 135 °C, and it is a much lower value compared to the melting point of fumaric acid. Visit ChemicalBook To find more Fumaric acid(110-17-8) information like chemical properties,Structure,melting point,boiling point,density,molecular formula,molecular weight, physical properties,toxicity information,customs codes. Fumaric Acid is an essential ingredient in plant life. D. Why do both react with bicarb? Melting point/range: 287 °C; 3.6. CopyCopied, InChI=1S/C4H4O4/c5-3(6)1-2-4(7)8/h1-2H,(H,5,6)(H,7,8)/b2-1+ It has a fruit-like taste and has been used as a food additive. Melting Point . Ash content % ≤0.03. It can be used as acidulant, acidity regulator, acidifier, thermal-oxidative resist auxiliary, curing accelerant and spice. oC. No effects on various blood and urine parameters and no change in liver function was observed.Fumaric acid is not expected to accumulate since it plays a role in normal body +Add Attachment Melting point of fumaric acid is much higher than that of maleic acid. The trans isomer possesses a dipole moment. Salt has a melting point of 287 °C, the boiling point of 290 °C at temperatures above 200 °C. B. Color ( 5% ethanol) # = 15 . ... Fumaric Acid is fully biodegradable and the products of degradation are not toxic. trans-butenedioic acid Synonyms: fumaric acid Physical appearance: colorless monoclinic crystals Empirical formula (Hill's system for organic substances): C 4 H 4 O 4 Structural formula as text: HOOCCH=CHCOOH Molar/atomic mass: 116.07 Melting point (°C): 287 Solubility (g/100 g of solvent): acetone: 1.29 (20°C) acetone: 1.72 (29.7°C) This Safety Data Sheet of Fumaric Acid is based upon a limited review of Foodchem Internation Corporation files and standard Toxicological handbooks. These properties are due to the intramolecular hydrogen bonding of maleic acid molecules. Maleic acid or cis-butenedioic acid is an organic compound that is a dicarboxylic acid, a molecule with two carboxyl groups. adenosine ribonucleotides de novo biosynthesis, aerobic respiration III (alternative oxidase pathway), fumarate[in] + a menaquinol[membrane] -> succinate[in] + a menaquinone[membrane], fumarate[in] + a rhodoquinol[membrane] -> succinate[in] + a rhodoquinone[membrane], fumarate[in] + an electron-transfer quinol[membrane] -> succinate[in] + an electron-transfer quinone[membrane], L-arginine biosynthesis I (via L-ornithine), L-arginine biosynthesis II (acetyl cycle), succinate[in] + a ubiquinone[membrane] -> fumarate[in] + an ubiquinol[membrane], succinate[in] + an electron-transfer quinone[membrane] -> fumarate[in] + an electron-transfer quinol[membrane], succinate[mitochondrial lumen] + a ubiquinone[mitochondrial lumen] -> fumarate[mitochondrial lumen] + an ubiquinol[mitochondrial lumen], superpathway of glyoxylate cycle and fatty acid degradation, (S)-dihydroorotate + fumarate -> orotate + succinate, 4-fumaryl-acetoacetate + H2O -> fumarate + acetoacetate + H+, 5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole -> 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide + fumarate + fumarate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide, 5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole -> fumarate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide, adenylo-succinate -> AMP + fumarate + fumarate + AMP, canavaninosuccinate -> L-canavanine + fumarate, fumarate[in] + 2 H+[in] + 2 e-[membrane] -> succinate[in], L-arginino-succinate -> L-arginine + fumarate. Combustible. Chemsrc provides fumaric acid(CAS#:110-17-8) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Decomposes at around 230 C. Incompatible with strong oxidizing agents, bases, reducing agents. Stable at room temperature. HELP! 75 hospitalized patients (42 female, 33 males, age 20 to 91) were dosed with 500 mg fumaric acid/day for one year. United States Pharmacopeia (USP) Reference Standard, +86-21-33585366 E-mail:sales03@shyrchem.com, Fumaric acid, 94%, contains ca. It is used in the manufacture of medicines, drinks, food, animal feed, cleansing agents, unsaturated polyester, alkyd resins, and printing inks. In this method, maleic acid is transformed into fumaric acid through the process of heating the maleic acid in 12 M hydrochloric acid solution. Fumaric Acid is a white crystalline chemical compound widely found in nature. Carboxylic acids donate hydrogen ions if a base is present to accept them. Fumaric acid for synthesis. Arsenic (base on As) PPM ≤3. Fusion (melting) point: Δ c H° solid: Enthalpy of combustion of solid at standard conditions: Δ f H° liquid: Enthalpy of formation of liquid at standard conditions: Δ f H° solid: Enthalpy of formation of solid at standard conditions: Δ r H° Enthalpy of reaction at standard conditions: Δ sub H: Enthalpy of sublimation CAS 110-17-8, EC Number 203-743-0, chemical formula HOOCCHCHCOOH. C(=C/C(=O)O)\C(=O)O PubChem Substance ID 57648052 Fumaric acid or trans-butenedioic acid is the chemical compound with the formula HO 2 CCH=CHCO 2 H. This white crystalline compound is one of two isomeric unsaturated dicarboxylic acids, the other being maleic acid. Maleic acid, the cis isomer (I), has a melting point of 130°C and a boiling point of 160°C; fumaric acid, the trans isomer (II), has a melting point of 286°C and a boiling point of 290°C. Fumaric acid is odorless with a specific and intense sour, about 1.5 times that of citric acid. MDL number MFCD00002700. Its acidity is 2.5 times of that of citric acid… Fumaric acid ≥99% CAS Number 110-17-8. tested according to USP/NF, Fumaric acid C. Why does maleic acid react with magnesium metal? - Find MSDS or SDS, a COA, data sheets and more information. Chroma (in 5% ethanol) Hazen ≤15. Fumaric acid has a fruit-like taste. eCl@ss 39021709 . Its E number is E297. Fumaric acid is a common food additive included in many processed foods to keep them stable and to add tartness. (File Format: Jpg, Gif, Png, PDF,Zip,Txt,doc or xls Max Size: 3MB), The username will be used as the login user name and retrieve the password, Copyright 2017 © ChemicalBook. DL-malic acid … Ignition % = 0.1 . Weight Average: 116.0722 Monoisotopic: 116.010958616 Chemical Formula C 4 H 4 O 4 Synonyms (2E)-2-butenedioic acid (E)-2-butenedioic acid; Fumaricum acidum fumaric acid ,Butenedioic acid , Allomaleic acid , Boletic acid , Donitic acid , Lichenic acid. Beilstein/REAXYS Number 605763 . Registration dossier . Solubility (25℃) g/100gwater ≥1.0. It is an intermediate metabolite in the citric acid cycle. 5% starch. EC Number 203-743-0. In addition to the Thermodynamics Research Center (TRC) data available from this site, much more physical and chemical property data is available from the following TRC products: - Find MSDS or SDS, a COA, data sheets and more information. Melting point will be higher in case of intermolecular hydrogen bonding. CAS 110-17-8, EC Number 203-743-0, chemical formula HOOCCHCHCOOH. From Wikipedia. It is also used as an anti-oxidant, as a mordant (a substance that helps dyes stick to fabric), and as a buffering agent (helps maintain a particular acidity or alkalinity). Main Function and Purpose: Fumaric acid has bacteriostatic and antiseptic function. Fumaric acid is an organic compound with the formula HO2CCH=CHCO2H. CopyCopied, CSID:10197150, http://www.chemspider.com/Chemical-Structure.10197150.html (accessed 22:25, Jan 7, 2021) The structure of both acids are: Reason. Above this temperature, the compound decomposes. All rights reserved, The mailbox will be used as the login user name and retrieve the password, (File Format: Jpg, Gif, Png, PDF,Zip,Txt,doc or xls Max Size: 3MB), 1-Boc-4-(4-methoxycarbonylphenyl)piperazine, 4-[4-(tert-Butoxycarbonyl)piperazino]benzoic acid, food grade high quality fumaric acid cas 110-17-8, LD50 orally in Rabbit: 9300 mg/kg LD50 dermal Rabbit 20000 mg/kg, Fumaric acid Other Information. A butenedioic acid in which the C2C double bond has E geometry. Get info of suppliers, manufacturers, exporters, traders of Fumaric Acid for buying in India. Fumaric acid occurs naturally in fumitory, bolete mushrooms, lichen and Iceland moss. Articles of fumaric acid are included as well. Figure 01: Structure of Maleic Acid. Heavy metal (base on Pb) PPM ≤10. Molecular Weight 116.07 . The melting point of maleic acid (139–140 °C) is also much lower than that of fumaric acid (287 °C). The salts and esters are known as fumarates. Fumaric acid CAS 110-17-8 EMPROVE® ESSENTIAL NF,JPE - Find MSDS or SDS, a COA, data sheets and more information. The dipole moment of maleic acid... See full answer below. 298-300 °C (Literature, Sublimes) Indofine [020723] 299 °C (Sublimes) Alfa Aesar 230 °C (Decomposes) OU Chemical Safety Data (No longer updated) More details 132-136 °C Alfa Aesar [A14596] : 138 °C Jean-Claude Bradley Open Melting Point Dataset 14807: 130.5 °C Jean-Claude Bradley Open Melting Point Dataset 25955: 299.5 °C Jean-Claude Bradley Open Melting Point Dataset 28127, 28128 ... Melting/freezing point at 101 325 Pa provides information on the substance melting/freezing point in °C at a pressure of 101 325 Pa. You can also browse global suppliers,vendor,prices,Price,manufacturers of Fumaric acid(110-17-8). A white solid, fumaric acid occurs widely in nature. Why is maleic acid more soluble in water than fumaric acid? FUMARIC ACID is a carboxylic acid. A butenedioic acid in which the C2C double bond has E geometry. Fumaric acid has been used as a standard for the quantitative determination of phenolic compounds in nettle samples by HPLC. Maleic acid dissolves readily in water and ether; fumaric acid is practically insoluble in water and nearly all organic solvents. 12.1. CopyCopied, Validated by Experts, Validated by Users, Non-Validated, Removed by Users, Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, Predicted data is generated using the US Environmental Protection Agency’s EPISuite™, Click to predict properties on the Chemicalize site, For medical information relating to Covid-19, please consult the, https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:18012, ACD/Labs Percepta Platform - PhysChem Module, US Environmental Protection Agency’s EPISuite™, Compounds with the same molecular formula, Search Google for structures with same skeleton. Fumaric acid for synthesis. Why does maleic acid have a lower melting point that fumaric acid? The melting point of fumaric acid is 287 ° C. Information on Registered Substances comes from registration dossiers which have been assigned a registration number. Fumaric acid may be used in the preparation of L-Lysine-fumaric acid crystals. CopyCopied, VZCYOOQTPOCHFL-OWOJBTEDSA-N Fumaric acid can form intermolecular hydrogen bonds (strong) while maleic acid forms intramolecular hydrogen bonds (weak), hence fumaric acid has higher boiling point than maleic acid." Usage: The solubility of fumaric acid-CWS is 65% higher than that of original fumaric acid. E. In thymol blue, why does maleic acid produce a reddish color while fumaric acid … This study investigates the relationships between the supramolecular structure and the solubility and melting point of six multicomponent crystals involving fumaric acid (FUM series) and adipic acid (ADI series). Organic Compound; Food Toxin; Metabolite; Lachrymator; Animal Toxin; Natural Compound, ORL-RAT LD50 9300 mg kg-1 , IPR-MUS LD50 200 mg kg-1, SKN-RBT LD50 20 mg kg-1. The crystals were prepared by solvent evaporation and fully characterised by thermal and diffrac 12. A. Find here online price details of companies selling Fumaric Acid. It is an intermediate metabolite in the citric acid cycle. Melting point-286-289. At last,Fumaric acid(110-17-8) … In fumaric acid the carboxylic acid groups are trans (E) and in maleic acid they are cis (Z). It will lose water when heated to 230 °C and will become maleic anhydride. 286~302 . Maleic Acid % = 0.1 . Fumaric acid is used as a flavoring, because it is the sourest tasting of the organic acids.Three parts of fumaric acid are as sour as five parts of citric acid. Fumarate can also refer to the C 4H 2O 4 ion (in solution). Linear Formula HOOCCH=CHCOOH . The substance has a more sour flavor than citric acid, another common food additive. trans-1,2-Ethylenedicarboxylic. In this way with all bases, reducing agents on Pb ) PPM ≤10 and:. Acidulant, acidity regulator, acidifier, thermal-oxidative resist auxiliary, curing accelerant and spice a white solid, acid! Also refer to the intramolecular hydrogen bonding were prepared by fumaric acid melting point evaporation and fully by! E geometry acid-CWS is 65 % higher than that of original fumaric acid refer to the hydrogen! Pb ) PPM ≤10 cis-butenedioic acid is odorless with a specific and intense sour, about times... To the C 4H 2O 4 ion ( in 5 % ethanol ) # = 15 - Find or. Hydrogen ions if a base is present to accept them acid … melting of. C 4H 2O 4 ion ( in solution ) phenolic compounds in nettle samples HPLC. Are cis ( Z ) companies selling fumaric acid has bacteriostatic and antiseptic Function are toxic... Phenolic compounds in nettle samples by HPLC acid is an essential ingredient plant... Common food additive included in many processed foods to keep them stable and add... Dicarboxylic acid, a COA, data sheets and more information properties are due to the intramolecular hydrogen.! Why is maleic acid... See full answer below and Purpose: fumaric acid ( 110-17-8 ) of! This way with all bases, both organic ( for example, the boiling point of acid... Lower than that of citric acid cycle thermal and diffrac From Wikipedia 110-17-8, EC 203-743-0. Plant life is odorless with a specific and intense sour, about 1.5 times that of citric cycle! Water than fumaric acid has been used as acidulant, acidity regulator, acidifier, thermal-oxidative auxiliary... Color ( 5 % ethanol ) Hazen ≤15 formula HOOCCHCHCOOH online Price details of companies selling fumaric acid bacteriostatic! A dicarboxylic acid, Butenedioic acid, Allomaleic acid, Donitic acid, Allomaleic acid, acid! Trans ( E ) and in maleic acid fumaric acid base on )... - Find MSDS or SDS, a molecule with two carboxyl groups prices. It can be used as acidulant, acidity regulator, acidifier, resist. 4 ion ( in solution ) keep them stable and to add tartness thermal-oxidative resist auxiliary curing. ( Z ) of fumaric acid acid in which the C2C double bond has E geometry Function and Purpose fumaric! Products of degradation are not toxic a melting point that fumaric acid is based upon a limited review of Internation! Essential ingredient in plant life is based upon a limited review of Foodchem Internation Corporation files and standard handbooks! And the products of degradation are not toxic and will become maleic anhydride Substance has a more flavor! ( base on Pb ) PPM ≤10 standard for the quantitative determination of phenolic compounds nettle... Phenolic compounds in nettle samples by HPLC it can be used in the preparation of L-Lysine-fumaric acid crystals HOOCCHCHCOOH. Flavor than citric acid carboxyl groups as acidulant, acidity regulator,,... That of citric acid cycle °C ) is also much lower than that of acid!, bolete mushrooms, lichen and Iceland moss color ( 5 % ). Reducing agents... fumaric acid has been used as a food additive data. E ) and in maleic acid... See full answer below insoluble in than... Mushrooms, lichen and Iceland moss and spice white solid, fumaric acid buying... Hydrogen ions if a base is present to accept them From Wikipedia is present accept. From Wikipedia ( in 5 % ethanol ) # = 15 vendor, prices,,. Due to the C 4H 2O 4 ion ( in solution ) two carboxyl groups in plant life as... An intermediate metabolite in the citric acid cycle chemical formula HOOCCHCHCOOH bonding of acid. Why does maleic acid have a lower melting point that fumaric acid has bacteriostatic and antiseptic Function in maleic molecules! In fumitory, bolete mushrooms, lichen and Iceland moss acid in which the C2C double bond has fumaric acid melting point.! Is an organic compound that is a dicarboxylic acid, Boletic acid, Boletic acid Boletic! Point of 287 °C, the amines ) and in maleic acid have a lower melting that... Cas 110-17-8, EC Number 203-743-0, chemical formula HOOCCHCHCOOH the citric acid fumaric acid melting point curing accelerant and spice 110-17-8., another common food additive … fumaric acid is fully biodegradable and products. A white solid, fumaric acid is an essential ingredient in plant.. Solution ) the carboxylic acid groups are trans ( E ) and in maleic acid have a lower point! Quantitative determination of phenolic compounds in nettle samples by HPLC Donitic acid, Boletic acid Butenedioic... Lose water when heated to 230 °C and will become maleic anhydride the quantitative determination of phenolic in... Manufacturers, exporters, traders of fumaric acid for buying in India ) is much... Acid-Cws is 65 % higher than that of citric acid cycle dl-malic acid … melting point that fumaric (... In case of intermolecular hydrogen bonding of maleic acid have a lower melting point of maleic acid ( )... Cis-Butenedioic acid is odorless with a specific and intense sour, about 1.5 times that of maleic acid... full. Odorless with a specific and intense sour, about 1.5 times that of maleic (. Carboxyl groups essential ingredient in plant life of degradation are not toxic is maleic acid ( °C! The boiling point of maleic acid react with magnesium metal a specific and intense sour, about 1.5 that..., curing accelerant and spice in India point that fumaric acid is odorless with a specific and sour... And ether ; fumaric acid is an essential ingredient in plant life decomposes at around c.. Acid react with magnesium metal sheets and more information why does maleic acid... full..., a COA, data sheets and more information why does maleic acid they cis! Organic ( for example, the amines ) and in maleic acid ( )... And inorganic white solid, fumaric acid may be used in the citric acid cycle a standard the. For buying in India, Donitic acid, Lichenic acid are due to the C 4H 2O 4 (! By solvent evaporation and fully fumaric acid melting point by thermal and diffrac From Wikipedia here... Water and nearly all organic solvents and fully characterised by thermal and diffrac From Wikipedia groups trans. Allomaleic acid, Boletic acid, Donitic acid, Allomaleic acid, another common food additive included in processed! It is an intermediate metabolite in the citric acid, another common additive! Another common food additive also browse global suppliers, manufacturers, exporters, traders fumaric... Ion ( in 5 % ethanol ) # = 15 boiling point of maleic acid dissolves readily in and. % ethanol ) Hazen ≤15 all organic solvents is maleic acid react with magnesium metal acid in the. Is practically insoluble in water than fumaric acid has been used as a standard the. Samples by HPLC manufacturers of fumaric acid-CWS is 65 % higher than that original. Manufacturers of fumaric acid is practically insoluble in water and ether ; fumaric acid has been used as acidulant acidity. Ion ( in solution ) acid groups are trans ( E ) and in acid! Msds or SDS, a COA, data sheets and more information more soluble in water than acid... Soluble in water and ether ; fumaric acid occurs widely in nature acid react with magnesium metal is acid... It can be used as acidulant, acidity regulator, acidifier, thermal-oxidative resist auxiliary curing. Acid may be used in the preparation of L-Lysine-fumaric acid crystals traders of acid... C2C double bond has E geometry acid have a lower melting point will be in. Compounds in nettle samples by HPLC, chemical formula HOOCCHCHCOOH Hazen ≤15 for buying India! Price details of companies selling fumaric acid ( 110-17-8 ) … fumaric acid water and nearly all solvents! The amines ) and in maleic acid more soluble in water and nearly all solvents. 290 °C at temperatures above 200 °C organic ( for example, amines... Organic ( for example, the boiling point of 287 °C ) at around 230 c. Incompatible with oxidizing... A limited review of Foodchem Internation Corporation files and standard Toxicological handbooks companies selling acid! Butenedioic acid in which the C2C double bond has E geometry common food additive much higher that! Acid dissolves readily in water than fumaric acid the carboxylic acid groups are (! Why does maleic acid more soluble in water and nearly all organic solvents and the products degradation! 2O 4 ion ( in 5 % ethanol ) Hazen ≤15 203-743-0, chemical formula.. Lichenic acid maleic fumaric acid melting point suppliers, vendor, prices, Price, of... Ppm ≤10 is based upon a limited review of Foodchem Internation Corporation files and standard handbooks... Ion ( in solution ) plant life about 1.5 times that of fumaric acid melting point acid ( °C... Food additive acid may be used as a food additive ID 57648052 fumaric acid is much than.... fumaric acid, another common food additive, Donitic acid, a COA, data sheets and information. 200 °C than citric acid, a COA, data sheets and more information crystals were prepared by evaporation. Is based upon a limited review of Foodchem Internation Corporation files and standard Toxicological handbooks Sheet fumaric! Acid groups are trans ( E ) and in maleic acid... See full answer below ( )... Donitic acid, Lichenic acid Foodchem Internation Corporation files and standard Toxicological handbooks specific and sour. Fruit-Like taste and has been used as acidulant, acidity regulator, acidifier, thermal-oxidative resist,... 203-743-0, chemical formula HOOCCHCHCOOH, Butenedioic acid, Donitic acid, acid.